Researchers in ACP countries are facing a growing range of challenges. They are required to respond effectively to the demands of policy makers, private sector investors and donor agencies, farmers and other stakeholders in the agri-food chain. They are being asked to deliver research outputs that will improve agricultural productivity, food quality and food safety, in order to increase their countries competitiveness in global markets, and contribute to food security, poverty alleviation and sustainable development. At the same time, researchers must be socially and ethically responsible and contribute to the advancement of science and technology. As the demands for accountability increase and the levels of funding diminish, researchers need to prioritize and strategize their responses.